Nicole Mastrangelo

Nicole Mastrangelo is the IP Counsel at the Broad Institute, a premier biomedical and genomic research center affiliated with Harvard, MIT, and five Boston‑area hospitals. With a unique blend of scientific and legal expertise, Nicole plays a pivotal role in protecting and stewarding breakthrough innovations. Originally trained as a neuroscientist, Nicole’s first exposure to legal frameworks came through organizing lab‑animal studies under IACUC protocols. Drawing on that early experience, she pursued a Master’s in Legal Studies instead of the more common MBA route, before earning her J.D.—solidifying her pathway into IP law. In her current role, Nicole supports a highly diverse range of technologies—from assays and chemical compounds to biologics—by embedding herself within UDRF projects, attending design meetings, educating scientists, and preparing patent filings from start to finish. She leverages her classroom experience teaching an IP survey course for non‑lawyers, ensuring her explanations are clear and accessible, free of legalese. Nicole is committed to more than just filing patents—she builds trust with scientists by learning from them and becoming an honorary member of their group, which in turn empowers early intervention on IP matters and prevents missteps like premature disclosures. At Broad, she also navigates the challenge of balancing nonprofit-driven publication goals with strategic IP and licensing opportunities. Nicole works closely with her team to time continuation and divisional filings, aligning patent portfolios with the institute’s mission while maximizing future licensing and scientific impact. Beyond her role at Broad, Nicole teaches part-time at Northeastern Law and serves on the board of A Girl You Might Know, an artists’ rights foundation, demonstrating a strong commitment to community and interdisciplinary engagement.
• Suffolk University Law School - JD Doctor of Law
• Northeastern University School of Law - Master's Degree
• Northeastern University - Bachelor of Science